The day-night attack on Kyiv, Ukraine, by Russian forces and air attacks since the beginning of the Russian invasion — an update from Kramer and Tung

At least 483 Ukrainian children had been killed since the start of the Russian invasion, according to the president of the country, Volodymyr Zelensky. The number of children killed may be higher than what is estimated by other estimates.

In the past, Kyiv’s 3.6 million residents were startled out of bed and sent for cover. The overnight attack early Thursday left very little time for residents to take shelter, with air defenses colliding with missiles six minutes after the alarm sounded, the Kyiv military administration said.

Russian forces have changed the timing of bombardments, the combination of weapons used and the trajectories of missiles and drones, lately flying them low along riverbeds and through valleys to avoid detection, Ukrainian officials say.

Andrew E. Kramer and Nicole Tung were reporting from the Ukranian capital of Kyiv. More than one person contributed reporting from New York, Kyiv, and a few other places. Dmitriy Khavin contributed translation.

Residents were bombarded with 17 waves of aerial attacks at all hours in May.

Investigating a criminal investigation into the clinic and the administrators responsible for operating the shelter at the Krasnoyarskaya clinic

City officials opened a criminal investigation into the clinic and the administrators responsible for operating the shelter there, centered on whether the shelter was properly maintained and why it may have been inaccessible, Mr. Klitschko said. Police officers will now patrol bomb shelters during air raids to make sure they are open, he added.

Yaroslav found Natalya bleeding and a blue bag with family documents in the scene of an explosion, according to the report. His daughter, who was not injured, saw what happened to her mother, Yaroslav said.

Yaroslav said a lot of people were trying to get in. “People were knocking, knocking for a very long time,” he said, adding, “There were women and children and nobody opened it.”

A man who lives near the clinic and who gave his name as Yaroslav told the Ukrainian public broadcaster Suspilne that his 33-year-old wife, Natalya, was also killed after she and their 9-year-old daughter, Polina, were unable to get into the shelter.

The city’s military administration said some of the debris fell on a clinic and an adjacent building. The mother and child died when they attempted to get into a shelter at the clinic, according to two emergency workers who were not authorized to speak to the news media.