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Several local landmarks are being destroyed in the Southern California fires
Several landmarks in Los Angeles have been destroyed due to the wildfires in California, USA, including the ‘Will Rogers Ranch House’ and a bungalow-style beachside motel built by William Randolph Hearst. Several other landmarks have been damaged, including film studios, a charter high school and a Jewish community centre. Reportedly, the fires have caused the…
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Clinical classification of the genes is based on genome editing
A study has shown that genome-wide variant effect prediction using deep learning-derived splice scores is possible for breast cancer-predisposition gene variantsCADD-Splice-improving genome-wide variant effect prediction using deep learning-derived splice scores. The American College of Medical Genetics (ACMG)-AMP rule-based framework combines evidence from population, computational and predictive, segregation, functional and other data, with each contributing source…
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Data from the epigenetics will be used to uncovergene interactions
A machine-learning model for understanding epigenetic influences on chromatin-accessibility landscapes andcyte states of human and fetal cells was developed. The model was trained on chromatin-accessibility data from over 200 adult and fetal cell types with an aim to understand how different chromatin-accessibility ‘landscapes’ yield different states. It took around 8 h to complete, using eight…
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It is not safe and unproven to use human embryo editing against disease
Researchers have modelled the effects of simultaneous editing of a single variant associated with a disease on human gene-editing systems at hundreds of locations. They found, in some cases, editing a single variant associated with a disease can have strong effects and that editing up to ten genes associated with a disease can reduce its…
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100 years on, there is still a revolution in quantum mechanics
Lucy Mensing was a member of the same group as Erwin Heisenberg and worked out some of the first applications of his quantum-mechanical theory, historian Daniela Monaldi said. Mensing was able to explain the spectrum of the hydrogen atom, consisting of just one electron and a single protons, in the presence of an applied magnetic…
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The Legion Go S is the first authorized third-party SteamOS handheld
Lenovo has revealed that the Legion Go S is aimed at 20-watt performance, 30-watt, maybe even 40-watt configurable performance, which will likely offer higher performance than the 15-watt-and-below Steam Deck’s chip. A lead designer on the Steam Deck and steam OS said the new version of the operating system will ship after March, if you…
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Alienware has a new laptop with fans and light-up trackpads
Alienware has unveiled two new high-end laptops, ‘Area-51’ and ‘Aurora’, which it claims will “take the pain of desktop replacement to new heights”. The Area-51 laptop has a 15.6-inch QHD display with 3ms response time and up to 300Hz refresh while the Aurora laptop has a 12.2-inch QHD display with 3ms response time and up…
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Net Neutrality is ending in a bad way
A US federal appeals court has rejected the Federal Communications Commission (FCC)’s attempt to enforce net neutrality rules on internet service providers (ISPs). The three-judge panel found that the FCC does not have the authority to impose net neutrality rules on internet service providers. It was the first time a three-judge panel struck down a…
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The 39th US President Jimmy Carter is dead at the age of 100
The US Embassy in Tehran has been invaded and occupied by Iranian students. Over 50 Americans were held hostage for 444 days in Iran prior to Jimmy Carter’s presidency. Carter negotiated a nuclear arms deal with North Korea in 1994 and helped negotiate a peace deal between Israel and Palestine.
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The Wisconsin school attack is an exception, because most of the U.S. shootings are done by men
A 17-year-old female student has killed one and injured two other students in a shooting at a private school in the US state of Virginia, officials said on Monday. Police said that they have identified the shooter as a 15-year-old girl and are investigating a possible motive. She was taken into custody, police added.
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Meta wishes the US government would prevent OpenAI from morphing into a for-profit company
A lawsuit filed by former OpenAI executives against OpenAI and its parent company Meta Platforms has claimed that a ” proliferation of start-up ventures that are considered charitable until they are potentially profitable” could happen if OpenAI is not held accountable for its choice to form as a non-profit. It further suggested that “all for-profit…
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The structure of the dystrophin glycoprotein complex
The structure of dystrophin-associated proteins has been explained by non-uniform refinement (NLR) of the crystal structure of dystrophin and utrophin spectrin repeats. Researchers found that the NLR was effective in improving single-particle cryo- reconstruction. This is the first time NLR is being used to explain dystrophin-associated proteins. dystrophin, utrophin, and Utrophin have all been linked…
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Why Asia is leading in green materials
South Korea has ranked fifth in the field of materials science every year from 2019 to 2023, according to Nature’s ‘Nature Index’. Its proportion of materials science Share relative to its overall Nature Index output (49.7%), a figure higher than China (45.7%) and more than three times higher than that of the United States (15.4%).
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Immigration Surge has been largest in the U.S
The US government’s Census Bureau (B.O.) and the Centers for Diseases Control and Prevention (CDC) haveComparison of Census and Census-based Data for the US Post-World Wide Reimmigration Crisis. The C.B.O.’s recent estimates suggest that the foreign-born share of the US population reached about 16% in July 2020. However, some experts believe that the B.O.’s estimates…
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The world could solve a lot of its biggest problems using science
About 6,000 people around the world were surveyed for Nature’s survey on science advice. They were asked about the quality of routine science advice to governments and about advice during a crisis like the COVID-19 pandemic. Over 60% of respondents said that science advice fails to incorporate a diversity of people or viewpoints.
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Governments don’t use science to solve their biggest problems
A recent survey has found that over 60% of survey respondents said science advice fails to incorporate a diversity of people or viewpoints. Science advice needs to incorporate more expertise in the future, according to the survey by the International Network for Governmental Science Advice. The survey was conducted on behalf of Nature by two…
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Top consumer watchdog in the United States has a plan for dealing with data brokers
The Consumer Financial Protection Bureau’s (CFPB) proposed action aims to stop data brokers from enabling scammers, stalkers and spies to undermine US’ safety and security. The CFPB has proposed to regulate data brokers in the same way as credit reporting agencies. It would require data brokers to obtain explicit authorisation from people before sharing their…
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A Disgraceful Pardon
US President Joe Biden has pardoned his son Hunter Biden, who was convicted of lying on a firearms transaction record in 1993. The Brady Handgun Violence Prevention Act requires the registration of firearms used in crimes. Hunter had joined board of Burisma, a firearms distributor, in April 2013 after he was charged and sentenced for…
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There is a guide to the Nature Index
The Nature Index 2024 supplement is based on Nature Index database covering research articles published between 2015 and 2023. It shows at least one article from any of the two institutions can be tracked. The top rising Australian institutions are shown in the tables in this supplement as they change in adjusted Share from 2022,…
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Universities in Australia are forced to take stock due to falling enrolments and funding cuts
Australia’s international student population is “under threat” as it is under threat from the government’s planned cuts in research funding, according to an expert panel. The panel was chaired by Australian Council for Research and Development (ACRA) President Chris Crossley. Crossley said he is hopeful that the sector can build strength and that the suggested…
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Is the climate deal a breakthrough or a let-down?
Environmental activists and delegates at the Conference of the Parties (COP) in Azerbaijan’s capital Baku have criticised the US over its pledge to provide $12.2 billion in climate finance each year by 2030. “We’ll see…massive hole in global climate finance provided [by US] just as…climate impacts are intensifying and accumulating,” said Clare Shakya, head of…
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Concerns about proposed boundaries of the Earth system
A new study suggests that the de-limit state is not intended to help inform target-setting and groundwater is not intended to provide a target for sustainable groundwater pumping. The analysis was conducted based on global GLDAS and GRACE data, which showed broad trends in Groundwater Waters Salinity (GWS). However, groundwater extraction that may safely occur…
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Global warming is being taken more seriously by the revised historical record
We present an ensemble of 200 observation-based reconstructed time series, which is analogous to the CMIP6 models, for each target metric. An ensemble of 200 observational reconstructions is obtained where the input for each reconstruction contains a different error realization. 1 and 2 are based on the reconstructs ensembles obtained as described above (that is,…
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China is growing at a rapid rate and has half of the top 20 science cities in it
The University of Chinese Academy of Sciences (CAS) in Hefei, Anhui province, is China’s leading institute for physical sciences. The local branch of the University of Chinese Academy of Sciences (CAS), the Beijing-headquartered mega-institute that is the global leader in Nature Index, is very high in terms of their performance in relation to other leading…
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The impacts of the megafires in Australia
The data collected from site-level data from sites burnt in Australia’s 2019-2020 megafires was used for assessing biodiversity impacts of the fires. The data was collected from 62 projects, of which only one met all other criteria but reported responses that were not related to abundance or occurrence (effects of grazing on reproduction in one…