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Why is she in pain now that her disease has been cured?
US Food and Drug Administration (FDA) approved two gene therapy treatments for sickle-cell disease last year, including the first CRISPR-based genome-editing therapy the agency has ever authorized. Both stem-cell transplants and gene therapy require chemotherapy before the treatment. Three rounds of chemotherapy and other treatments drove her cancer into remission, but she still struggles with…
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Is CAR-T-cell therapy possible for children with cancer?
A US-based company has claimed that its CAR-T-cell therapy may help treat childhood cancers. Tessa Therapeutics said its CAR-T-cell therapy is being developed to treat children with brain, bone and other organ systems cancers. The company wants to use the cells as a substitute for chemotherapy and radiation for the treatment. However, it has not…
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A Crispr therapy is designed to attack tumors.
Scientists at University of Pennsylvania in the US have discovered a way to personalise cancer therapy by editing and transporting gene expression to cancerous cells. They infused the edited cells back into volunteers who had previously been treated with several rounds of chemotherapy. The edited cells travelled to the tumors and killed them.